@article {49562,
	title = {Iron mediated oxidative ring opening-homocoupling of cyclopropanols: facile access to 1,6-diketones},
	journal = {ChemistrySelect},
	volume = {10},
	year = {2025},
	month = {MAY},
	pages = {e202501745},
	type = {Article},
	abstract = {<p>
	We have developed a new approach for the synthesis of 1,6-diketones via iron-catalyzed ring opening of cyclopropanol with a nontoxic, inexpensive iron catalyst under open-air conditions. This method eliminates the need for additives and employs tert-butanol as an eco-friendly solvent. This methodology allows rapid access to a variety of symmetrical 1,6-diketones under mild conditions. Preliminary mechanistic studies revealed the involvement of radical pathways.</p>
},
	keywords = {1, 6-Diketone synthesis, C \& horbar, C bond cleavage, cyclopropanols, Homocoupling, Iron mediated},
	issn = {2365-6549},
	doi = {10.1002/slct.202501745},
	author = {Shinde, Ravi A. and Shirsath, Sachin and Muthukrishnan, M.}
}
@article {49677,
	title = {Nickel-catalyzed regioselective C--H alkynylation of pyridones and isoquinolinones using alkynyl bromides},
	journal = {ChemCatChem},
	volume = {17},
	year = {2025},
	month = {JUN},
	type = {Article},
	abstract = {<p>A straightforward and efficient protocol for the regioselective C \&amp; horbar;H alkynylation of 2-pyridones and isoquinolinones with bromoalkynes under nickel catalysis is described. The alkynylation reaction is enabled by a simple and inexpensive Ni(OTf)2/tBubpy catalyst system and uses easily accessible bromoalkynes. The protocol demonstrates a broad substrate scope with up to 95\% yield (42 examples) and accommodates synthetically valuable functionalities, such as halides, trifluoromethyl, nitrile, ether, thioether, alkyl silanes, and alkene, as well as heteroarene moieties like pyridinyl, furanyl, and thiophenyl. The pyridinyl directing group on alkynylated 2-pyridones can be smoothly removed to give C6-alkynylated free NH-pyridone. Preliminary mechanistic studies suggest that the alkynylation proceeds via a 2e- oxidative addition pathway involving crucial C \&amp; horbar;H activation.</p>
},
	keywords = {alkynylation, C \& horbar, H Activation, Mechanism, Nickel, pyridones},
	issn = {1867-3880},
	doi = {10.1002/cctc.202500338},
	author = {Verma, Suryadev K. and Patil, Harshal R. and Punji, Benudhar}
}
