@article { ISI:000270106700015,
	title = {Synthesis and in vitro study of 14-aryl-14H-dibenzo[a.j]xanthenes as cytotoxic agents},
	journal = {Bioorganic \& Medicinal Chemistry Letters},
	volume = {19},
	number = {19},
	year = {2009},
	month = {OCT},
	pages = {5590-5593},
	publisher = {PERGAMON-ELSEVIER SCIENCE LTD},
	address = {THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND},
	abstract = {<p>A simple and expedient method for the synthesis of a series of 14-aryl-14H-dibenzo[a.j]xanthenes is described through a one-pot condensation of beta-naphthol with aryl aldehydes catalysed by TaCl(5) under solvent-free conventional heating. The major advantages of the present method are: high yields, less reaction time, solvent-free condition and easy purification of the products. The synthesized 14-aryl-14H-dibenzo[a.j]xanthenes were evaluated against a panel of six human cancer lines of different tissues. Synthesized compound 30 showed IC(50) of 37.9 and 41.3 mu M against Colo-205 and 502713, respectively, whereas 3g showed IC(50) of 41.9 mu M against Colo-205. (C) 2009 Elsevier Ltd. All rights reserved.</p>},
	keywords = {Aldehyde, beta-Naphthol, condensation, Cytotoxicity, One-pot reaction, Solvent-free, Tantalum(V) chloride, Xanthenes},
	issn = {0960-894X},
	doi = {10.1016/j.bmcl.2009.08.033},
	author = {Bhattacharya, Asish K. and Rana, Kalpeshkumar C. and Mujahid, Mohammad and Sehar, Irum and Saxena, Ajit K.}
}
@article {49252,
	title = {One-pot synthesis of pyrazoles from sulfonyl hydrazides and alkynyl ketones using environmentally benign sulfonium iodate (I) reagent},
	journal = {ChemistrySelect},
	volume = {9},
	year = {2024},
	month = {OCT},
	pages = {e202403249},
	type = {Article},
	abstract = {<p>
	Pyrazole is an omnipresent moiety in many natural products and pharmaceutically active compounds. Here, we have developed a simple and dynamic method for one-pot synthesis of substituted pyrazoles through the intramolecular cyclization of hydrazides and alkynyl ketones, using a novel sulfonium saltbased iodate (\&amp; Iukcy;) reagent system. This method has the advantage that it proceeds in a one-pot, without isolating a less stable hydrazone intermediate. Hypervalent iodine-based reagents are an environmentally benign and greener option to toxic metal oxidants; they have an extensive application in metal-catalyst-free reactions, and this reaction proceeds in less time with high yields.</p>
},
	keywords = {Deprotonation, One-pot reaction, Oxidative iodination, Pyrazole, S(N)2-type cyclization},
	issn = {2365-6549},
	doi = {10.1002/slct.202403249},
	author = {Mishra, Akanksha and Talukdar, Mrinal and Krishna, Gamidi Rama and Begari, Eeshwaraiah}
}
