Cu-Catalyzed iminative hydroolefination of unactivated alkynes en route to 4-imino-tetrahydropyridines and 4-aminopyridines
| Title | Cu-Catalyzed iminative hydroolefination of unactivated alkynes en route to 4-imino-tetrahydropyridines and 4-aminopyridines |
| Publication Type | Journal Article |
| Year of Publication | 2016 |
| Authors | Kumar, R, Thorat, SH, Reddy, MSridhar |
| Journal | Chemical Communications |
| Volume | 52 |
| Issue | 92 |
| Pagination | 13475-13478 |
| Date Published | OCT |
| Abstract | A general method for synthesizing 4-imino tetrahydropyridine derivatives is achieved, from readily available beta-enaminones and sulfonyl azides, which comprises a sequential copper catalyzed ketenimine formation and its hitherto inaccessible intramolecular hydrovinylation. The products are shown as ready precursors for highly valuable 4-sulfonamidopyridine derivatives via DDQ mediated oxidation. |
| DOI | 10.1039/c6cc08081b |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 6.567 |
Divison category:
Center for Material Characterization (CMC)