Cu(OTf)(2) catalyzed Biginelli type condensation of aldehydes, beta-keto esters and carbamates: synthesis of 3,4-dihydro[1,3]oxazin-2-ones
| Title | Cu(OTf)(2) catalyzed Biginelli type condensation of aldehydes, beta-keto esters and carbamates: synthesis of 3,4-dihydro[1,3]oxazin-2-ones |
| Publication Type | Journal Article |
| Year of Publication | 2008 |
| Authors | Jagdale, AR, Paraskar, AS, Sudalai, A |
| Journal | Indian Journal of Chemistry Section B-Organic Chemistry including Medicinal Chemistry |
| Volume | 47 |
| Issue | 7 |
| Pagination | 1091-1095 |
| Date Published | JUL |
| Type of Article | Article |
| ISSN | 0376-4699 |
| Keywords | aldehydes, Catalysts, Copper, Multicomponent reaction |
| Abstract | Cu(OTf)(2) catalyzes effectively a new multicomponent reaction comprising aldehydes, beta-ketoester and methy carbamate in acetonitrile to afford substituted 3,4-dihydro[1,3]oxazin-2-ones in 60-82% yields. These compounds have been found to show inhibition activity against HL-60 cancer cell. |
| Type of Journal (Indian or Foreign) | Indain |
| Impact Factor (IF) | 0.471 |
Divison category:
Chemical Engineering & Process Development