Efficient total synthesis of calothrixin B
| Title | Efficient total synthesis of calothrixin B |
| Publication Type | Journal Article |
| Year of Publication | 2012 |
| Authors | Bhosale, SM, Gawade, RL, Puranik, VG, Kusurkar, RS |
| Journal | Tetrahedron Letters |
| Volume | 53 |
| Issue | 23 |
| Pagination | 2894-2896 |
| Date Published | JUN |
| ISSN | 0040-4039 |
| Keywords | Calothrixin B, CAN, DMF-methanol, Hydride donor |
| Abstract | An efficient synthesis of calothrixin B (2) is demonstrated starting from 9H-carbazol-4-ol, having two one-pot reaction sequences as key steps. As a novel observation, DMF-methanol was shown to be a hydride donor for reduction of aldehyde to alcohol. Unexpectedly, nucleophilic substitution of benzyloxy by methoxy group was observed. (C) 2012 Elsevier Ltd. All rights reserved. |
| DOI | 10.1016/j.tetlet.2012.03.131 |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 2.397 |
Divison category:
Physical and Materials Chemistry