Formal synthesis of (-)-stemoamide using a useful epimerization at C-8
| Title | Formal synthesis of (-)-stemoamide using a useful epimerization at C-8 |
| Publication Type | Journal Article |
| Year of Publication | 2012 |
| Authors | Chavan, SP, Harale, KR, Puranik, VG, Gawade, RL |
| Journal | Tetrahedron Letters |
| Volume | 53 |
| Issue | 21 |
| Pagination | 2647-2650 |
| Date Published | MAY |
| ISSN | 0040-4039 |
| Keywords | Allylation, Allylic oxidation, Pyroglutamic acid, Ring closing metathesis, Stemoamide |
| Abstract | The formal synthesis of (-)-stemoamide was achieved starting from L-pyroglutamic acid. The key steps used are the allylation using BF3 center dot OEt2, ring closing metathesis, allylic oxidation and a novel epimerization at C8. (C) 2012 Elsevier Ltd. All rights reserved. |
| DOI | 10.1016/j.tetlet.2012.03.054 |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 2.397 |
Divison category:
Center for Material Characterization (CMC)
Organic Chemistry