Highly concise and practical route to clavaminols, sphinganine and (+)-spisulosine via indium mediated allylation of alpha-hydrazino aldehyde and a theoretical insight into the stereochemical aspects of the reaction
| Title | Highly concise and practical route to clavaminols, sphinganine and (+)-spisulosine via indium mediated allylation of alpha-hydrazino aldehyde and a theoretical insight into the stereochemical aspects of the reaction |
| Publication Type | Journal Article |
| Year of Publication | 2013 |
| Authors | Pandey, M, Chowdhury, PSarathi, Dutta, AKumar, Kumar, P, Pal, S |
| Journal | RSC Advances |
| Volume | 3 |
| Issue | 35 |
| Pagination | 15442-15448 |
| Date Published | JUL |
| ISSN | 2046-2069 |
| Abstract | A conceptually different approach has been employed for the synthesis of 1,2-amino alcohols by proline-catalyzed alpha-amination of aldehyde and one-pot indium mediated allylation of the crude alpha-hydrazino aldehydes. DFT based quantum chemical calculations have been performed to obtain a quantitative explanation of the stereoselectivity of the reaction. |
| DOI | 10.1039/c3ra43048k |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 3.708 |
Divison category:
Organic Chemistry
Physical and Materials Chemistry