Metal-free regioselective cross dehydrogenative coupling of cyclic ethers and aryl carbonyls
| Title | Metal-free regioselective cross dehydrogenative coupling of cyclic ethers and aryl carbonyls |
| Publication Type | Journal Article |
| Year of Publication | 2019 |
| Authors | Mane, KD, Mukherjee, A, Vanka, K, Suryavanshi, G |
| Journal | Journal of Organic Chemistry |
| Volume | 84 |
| Issue | 4 |
| Pagination | 2039-2047 |
| Date Published | FEB |
| Type of Article | Article |
| ISSN | 0022-3263 |
| Abstract | A highly regioselective, efficient, and metal-free oxidative cross dehydrogenative coupling (CDC) of aryl carbonyls with cyclic ethers has been developed. This method offers easy access to substituted alpha-arylated cyclic ethers with a high functional group tolerance in good to excellent yields. The regioselectivity of this CDC reaction was confirmed by density functional theory (DFT)-based calculations. |
| DOI | 10.1021/acs.joc.8b03048 |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 4.745 |
Divison category:
Chemical Engineering & Process Development
Physical and Materials Chemistry