New route to eremophilanes: synthesis of (+/-)-eremophilenolide, (+/-)-eremophiledinone, and (+/-)-deoxyeremopetasidione
| Title | New route to eremophilanes: synthesis of (+/-)-eremophilenolide, (+/-)-eremophiledinone, and (+/-)-deoxyeremopetasidione |
| Publication Type | Journal Article |
| Year of Publication | 2008 |
| Authors | Srinivas, P, D. Reddy, S, K. Kumar, S, Dubey, PK, Iqbal, J, Das, P |
| Journal | Tetrahedron Letters |
| Volume | 49 |
| Issue | 42 |
| Pagination | 6084-6086 |
| Date Published | OCT |
| Abstract | A new and efficient route to the family of eremophilanes is reported. Key steps are the highly stereocontrolled Diels-Alder reaction and aldol condensation to furnish a cis-decalin system with the desired stereochemistry present in the eremophilane family of natural products. This approach is general and was utilized for the synthesis of (+/-)-eremophilenolide, (+/-)-eremophiledinone, and (+/-)-deoxyeremopetasidione. (C) 2008 Elsevier Ltd. All rights reserved. |
| DOI | 10.1016/j.tetlet.2008.08.006 |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 2.347 |
Divison category:
Organic Chemistry