Organocatalytic asymmetric synthesis of (-)-delta-coniceine based on sequential proline-catalyzed asymmetric alpha-amination-HWE olefination
| Title | Organocatalytic asymmetric synthesis of (-)-delta-coniceine based on sequential proline-catalyzed asymmetric alpha-amination-HWE olefination |
| Publication Type | Journal Article |
| Year of Publication | 2010 |
| Authors | Panchgalle, SP, Bidwai, HB, Chavan, SP, Kalkote, UR |
| Journal | Tetrahedron-Asymmetry |
| Volume | 21 |
| Issue | 19 |
| Pagination | 2399-2401 |
| Date Published | OCT |
| ISSN | 0957-4166 |
| Abstract | An efficient asymmetric synthesis of (-)-delta-coniceine via sequential proline-catalyzed asymmetric alpha-amination and Horner-Wadsworth-Emmons olefination of an aldehyde with excellent enantiomeric excess (>99%) and high yields (overall yield 44%) is described. (C) 2010 Elsevier Ltd. All rights reserved. |
| DOI | 10.1016/j.tetasy.2010.08.009 |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 2.484 |
Divison category:
Organic Chemistry