Regioselective and diastereoselective iodocyclization reaction of alkene-thioureas: an efficient approach to bicyclic beta-lactams
| Title | Regioselective and diastereoselective iodocyclization reaction of alkene-thioureas: an efficient approach to bicyclic beta-lactams |
| Publication Type | Journal Article |
| Year of Publication | 2015 |
| Authors | Garud, DR, Sonawane, AD, Auti, JB, Rode, ND, Ranpise, VR, Joshi, RR, Joshi, RA |
| Journal | New Journal of Chemistry |
| Volume | 39 |
| Issue | 12 |
| Pagination | 9422-9428 |
| Date Published | SEP |
| ISSN | 1144-0546 |
| Abstract | Bicyclic beta-lactams, i.e. 3-thia-1-dethiacephams, were synthesized via a highly regioselective and diastereoselective iodocyclization reaction of alkene-thioureas with molecular iodine. Furthermore, the structure of 3-thia-1-dethiacepham was confirmed by a chemical method, the dehydrohalogenation reaction using DBU. |
| DOI | 10.1039/c5nj01963j |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 3.277 |
Divison category:
Organic Chemistry