Regioselective NaBH4 and DIBAL-H reductions of 3,4-dimethoxyhomopiperonylphthalimide: concise and efficient synthesis of nuevamine and isonuevamine
| Title | Regioselective NaBH4 and DIBAL-H reductions of 3,4-dimethoxyhomopiperonylphthalimide: concise and efficient synthesis of nuevamine and isonuevamine |
| Publication Type | Journal Article |
| Year of Publication | 2011 |
| Authors | Wakchaure, PB, Kunte, SS, Argade, NP |
| Journal | Indian Journal of Chemistry Section B-Organic Chemistry Including Medicinal Chemistry |
| Volume | 50 |
| Issue | 6 |
| Pagination | 868-871 |
| Date Published | JUN |
| ISSN | 0376-4699 |
| Keywords | 6-dimethoxyhomophthalimide, intramolecular dehydrative cyclizations, isonuevamine, N-Homopiperonyl-5, nuevamine, regioselective reductions, synthesis |
| Abstract | Facile synthesis of nuevamine and isonuevamine has been reported via the regioselectivc reduction of hindered and unhindered carbonyl groups of 3,4-dimethoxyhomopiperonylphthalimide, respectively using sodium borohydridc and diisobutylaluminum hydride, Mowed by an acid catalyzed intramolecular dehydrative cyclization pathways. The chemistry involved in obtaining the regioselectivity has been discussed in brief. |
| Type of Journal (Indian or Foreign) | Indian |
| Impact Factor (IF) | 0.891 |
Divison category:
Organic Chemistry