Solution-phase synthesis of the macrocyclic core of teixobactin
| Title | Solution-phase synthesis of the macrocyclic core of teixobactin |
| Publication Type | Journal Article |
| Year of Publication | 2016 |
| Authors | Dhara, S, Gunjal, VB, Handore, KL, D. Reddy, S |
| Journal | European Journal of Organic Chemistry |
| Volume | 25 |
| Pagination | 4289-4293 |
| Date Published | SEP |
| Abstract | Towards the total chemical synthesis of the exceptionally potent antibiotic teixobactin, we synthesized the macrocyclic core of a natural product by using a solution-phase approach. The gramscale synthesis of L-allo-enduracididine and Shiina macrolactonization are highlights of the present disclosure. |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 3.068 |
Divison category:
Organic Chemistry