2-Aroylindoles from o-bromochalcones via Cu(I)-catalyzed SNAr with an azide and intramolecular nitrene C-H insertion
| Title | 2-Aroylindoles from o-bromochalcones via Cu(I)-catalyzed SNAr with an azide and intramolecular nitrene C-H insertion |
| Publication Type | Journal Article |
| Year of Publication | 2014 |
| Authors | Goriya, Y, Ramana, CV |
| Journal | Chemical Communications |
| Volume | 50 |
| Issue | 58 |
| Pagination | 7790-7792 |
| Date Published | May |
| Type of Article | Article |
| ISSN | 1359-7345 |
| Abstract | A simple procedure for the synthesis of 2-aroylindole derivatives comprising a one-pot CuI-catalyzed SNAr reaction of o-bromochalconeswith sodium azide and subsequent intramolecular cyclization through nitrene C-H insertion has been developed. This protocol is also applicablewith the 2'-bromocinnamates giving the indole-2-carboxylates. |
| DOI | 10.1039/c4cc02501f |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 6.567 |
Divison category:
Organic Chemistry