Iminium ion cascade reaction in the total synthesis of (+)-vincadifformine
| Title | Iminium ion cascade reaction in the total synthesis of (+)-vincadifformine |
| Publication Type | Journal Article |
| Year of Publication | 2011 |
| Authors | Pandey, G, Kumara, PC |
| Journal | Organic Letters |
| Volume | 13 |
| Issue | 17 |
| Pagination | 4672-4675 |
| Date Published | SEP |
| ISSN | 1523-7060 |
| Abstract | An iminium ion triggered cascade reaction is described in the total synthesis of (+)-vincadifformine by the coupling of 3,3-substituted tetrahydropyridine and indole derivative. The strategy allows simultaneous construction of two new rings, three new sigma bonds, and two new stereogenic centers in one pot with complete stereochemical control. |
| DOI | 10.1021/ol201892j |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 6.17 |
Divison category:
Organic Chemistry