General and efficient route to 3 `-deoxy-3 `-N-, S-, and C-substituted altropyranosyl thymines from 2',3'-O-anhydro-mannopyranosylthymine
| Title | General and efficient route to 3 `-deoxy-3 `-N-, S-, and C-substituted altropyranosyl thymines from 2',3'-O-anhydro-mannopyranosylthymine |
| Publication Type | Journal Article |
| Year of Publication | 2007 |
| Authors | Deshpande, SG, Pathak, T |
| Journal | Tetrahedron |
| Volume | 63 |
| Issue | 3 |
| Pagination | 602-608 |
| Date Published | JAN |
| Type of Article | Article |
| ISSN | 0040-4020 |
| Abstract | An efficient route to 1-(2,3-O-anhydro-4,6-O-phenylmethylene–D-mannopyranosyl) thymine from 1,2,4,6-tetra-O-acetyl-3-O-tosyl-beta-D-glucopyranose has been devised. This newly synthesized epoxide is opened up regioselectively at the C-3'-position by N-, S-, and C-nucleophiles to afford a wide range of new 3-deoxy-3'-substituted altropyranosyl thymines. (c) 2006 Published by Elsevier Ltd. |
| DOI | 10.1016/j.tet.2006.11.025 |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 2.645 |
Divison category:
Organic Chemistry